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  • Title: Induction of hepatic malic enzyme in response to insulin.
    Author: Thompson EW, Drake RL.
    Journal: Mol Cell Endocrinol; 1982 May; 26(3):309-14. PubMed ID: 7042415.
    Abstract:
    The activity and quantity of hepatic malic enzyme were determined in diabetic rats at various times after insulin treatment. The increase in activity observed following insulin treatment was accompanied by a similar increase in the quantity of this enzyme, as determined by a specific radioimmunoassay. These results demonstrate that the insulin-mediated increase in malic enzyme activity was due to an increase in the quantity of enzyme and did not involve a modification of existing enzyme molecules.
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