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  • Title: [Radical surgical correction of tetralogy of Fallot: comparison between the effects of isoproterenol in IPPV and spontaneous-ventilation after surgical treatment (author's transl)].
    Author: Clementi G, Memè M, Burchiani M, Coletta R, Di Tizio S, Punzo S, Pisani E.
    Journal: G Ital Cardiol; 1981; 11(10):1472-6. PubMed ID: 7042437.
    Abstract:
    The AA. studied 7 patients affected by Tetralogy of Fallot; their ages were between 4 and 20 years. At the end of the radical surgical correction we studied their haemodynamics. From the analysis of the data we found that using beta-agonist drugs (Isuprel 0.05 mcg x Kg x min) there were no change in the haemodynamic data when the patients were kept under positive pressure ventilation. In spontaneous ventilation we observed that the same data can raise the cardiac index of 22%, lower the total peripheral resistances (20%) and the pulmonary vascular resistances (8%) and the intrapulmonary shunt (8%).
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