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  • Title: Hepatic vagotomy (partial hepatic denervation) does not alter ingestive responses to metabolic changes.
    Author: Tordoff MG, Hopfenbeck J, Novin D.
    Journal: Physiol Behav; 1982 Mar; 28(3):417-24. PubMed ID: 7043507.
    Abstract:
    The effects of transecting the hepatic branch of the vagus nerve were studied in male and female Long Evans rats. No differences between same-sex hepatic vagotomized (HV) and sham operated (SHM) animals were found in postoperative body weight, diurnal patterns of ingestion, or the response to insulin (4, 8, 12 U/kg, IP), 2-deoxy-D-glucose (125, 250, 500 mg/kg, IP), sodium chloride (10 ml/kg: 0.5, 1.0, 2.0 M, IP), or polyethylene glycol (10 ml/kg: 30% w/v, SC). These results can be interpreted as evidence for a minor role of the hepatic vagus in the total complement of hepatic afferent innervation.
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