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  • Title: Validation of cardiac output estimates by digital video subtraction angiography in dogs. Correlation with thermodilution values.
    Author: Carey PH, Slutsky RA, Ashburn WL, Higgins CB.
    Journal: Radiology; 1982 Jun; 143(3):623-6. PubMed ID: 7043645.
    Abstract:
    To determine the validity of cardiac output estimates obtained by digital video subtraction angiography (DVSA), they were compared with thermodilution values in 6 anesthetized dogs. Multiple levels of cardiac output were produced in each dog by graded openings of peripheral arteriovenous fistulas. Both direct contrast and mask-mode images were evaluated. There was good correlation between thermodilution and direct contrast values (r = 0.88) as well as between thermodilution and mask-mode values (r = 0.89), though the mask-mode outputs were 12 +/- 1.1% less than the direct contrast values (p less than 0.05). Direct contrast and mask-mode values correlated well (n = 6; r greater than or equal to 0.95). Digital outputs exhibited little variation, indicating excellent reproducibility. These results demonstrate the validity of area-length estimates of cardiac output by DVSA.
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