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  • Title: Affinity change of the adipocyte receptor fails to alter insulin-stimulated glucose transport.
    Author: McCaleb ML, Donner DB.
    Journal: Biochem J; 1982 Jan 15; 202(1):263-5. PubMed ID: 7044377.
    Abstract:
    Occupancy increased the affinity of the insulin receptor of the adipocyte. During the affinity change the half-maximal sensitivity of glucose transport to insulin stimulation was unaltered. Decreased maximum response of transport only occurred after the affinity change. There was not a simple relationship between receptor affinity and insulin stimulation of glucose transport in the adipocyte.
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