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  • Title: Evaluation of the role of the Treponema pallidum immobilisation test in Britain.
    Author: Sprott MS, Selkon JB, Turner RH.
    Journal: Br J Vener Dis; 1982 Jun; 58(3):147-8. PubMed ID: 7044470.
    Abstract:
    After specimens of sera from 100000 patients had been screened by a reagin and Treponema pallidum haemagglutination assay (TPHA) 2.7% required further examination. The fluorescent treponemal antibody-absorption (FTA-ABS) test confirmed either a negative or positive TPHA result in 95% of the samples, so that no further investigations were required. This accounted for 99% of the specimens submitted to the laboratory. Repeat tests on a further sample resolved many of the remaining discrepancies. Only 0.05% of patients, in whom repeat tests confirmed a positive TPHA but a negative FTA-ABS result, benefited from a TPI test.
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