These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Fatty acid activation and temperature perturbation of rat brain microsomal phospholipase D.
    Author: Chalifour R, Kanfer JN.
    Journal: J Neurochem; 1982 Aug; 39(2):299-305. PubMed ID: 7045286.
    Abstract:
    The hydrolytic and transphosphatidylation activities of rat brain microsomal phospholipase D were highly latent in the absence of an appropriate activator. The most suitable surfactants for this activation were oleate and palmitoleate. Besides the bile acids and unsaturated fatty acids, other naturally occurring surfactants, such as lysophospholipids, acidic phospholipids, acyl-CoA's, and gangliosides, were inactive. Taurodeoxycholate, at optimal concentration, produced a profound inhibition of oleate activation. Phospholipase D activity was detectable in all rat tissues investigated. The optimal incubation temperature for phospholipase D was 30 degrees C, with a break point at 16.1 degrees C in an Arrhenius plot.
    [Abstract] [Full Text] [Related] [New Search]