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  • Title: Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections.
    Author: de Jersey P, Wooller HO.
    Journal: Med J Aust; 1982 Mar 20; 1(6):267-8. PubMed ID: 7045606.
    Abstract:
    A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections. The symptomatic response was 73% for both drugs. Bacterial eradication was achieved in 81% and 100% of patients receiving cinoxacin and co-trimoxazole respectively. Three patients receiving co-trimoxazole stopped treatment because of adverse reactions. We conclude that cinoxacin is an effective and safe antibacterial agent in the treatment of urinary tract infections.
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