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  • Title: Effect of single-dose prophylactic co-trimoxazole on the incidence of gynaecological postoperative urinary tract infection.
    Author: Ireland D, Tacchi D, Bint AJ.
    Journal: Br J Obstet Gynaecol; 1982 Jul; 89(7):578-80. PubMed ID: 7046784.
    Abstract:
    One hundred patients having abdominal hysterectomy for benign conditions were randomized into two groups; 50 received co-trimoxazole by intramuscular injection immediately before operation and a control group of 50 were given no antibacterial cover. Single-dose chemoprophylaxis with co-trimoxazole was effective in reducing the incidence of postoperative urinary tract infection from 35% in the control group to 4% in the treated group.
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