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  • Title: Preoperative and postoperative renin levels in coarctation of the aorta.
    Author: Parker FB, Streeten DH, Farrell B, Blackman MS, Sondheimer HM, Anderson GH.
    Journal: Circulation; 1982 Sep; 66(3):513-4. PubMed ID: 7046989.
    Abstract:
    We studied plasma renin activity (PRA) in eight children before and after surgical correction of aortic coarctation. These eight children underwent a combination of low-sodium diet and diuresis before surgery, and PRA was measured shortly thereafter. Thirty-two to 51 months after successful surgical correction, PRA was measured again. The mean PRA was 21.4 +/- 1.3 ng/ml/hour (+/- SD) preoperatively and 5.5 +/- 1.5 ng/ml/hour postoperatively. These findings provide further evidence of the significance of increased renin-angiotensin activity in patients with aortic coarctation.
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