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  • Title: Pleural effusion in lung cancer.
    Author: Sahn SA.
    Journal: Clin Chest Med; 1982 May; 3(2):443-52. PubMed ID: 7047062.
    Abstract:
    Pleural effusions are common in the setting of lung cancer. The clinician must establish whether the effusion is malignant, ruling out the possibility of curative surgery; paramalignant, which may or may not rule out surgery; or unassociated with the cancer. A pleural effusion associated with lung cancer is an ominous finding, but a small percentage of patients in this setting will be candidates for curative surgery. When a malignant pleural effusion is diagnosed by cytology or histology, the clinician must decide on the most appropriate form of palliative therapy for the symptomatic patient. In the symptomatic patient with a reasonable life expectancy, chest tube drainage with the instillation of tetracycline hydrochloride appears to be the most effective and least morbid form of palliative therapy.
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