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  • Title: A case report of pseudohypoparathyroidism (Drezner's type I) associated with probable Bartter's syndrome.
    Author: Iba K, Morii H, Wada M, Yasumoto R, Kishimoto T, Mitsuhashi T, Hojo K, Okahara T.
    Journal: Endocrinol Jpn; 1981 Oct; 28(5):595-604. PubMed ID: 7047153.
    Abstract:
    A 24-yr-old male patient that suffered from chronic tetany since school age. At the age of 20 tetanic convulsions occurred due to hypocalcemia. His mother also had chronic tetany due to pseudohypoparathyroidism. At the age of 24, hypocalcemia caused by pseudohypoparathyroidism was noted. Hypopotassemia persisted even when the hypocalcemia improved with the administration of 1 alpha-hydroxycholecalciferol and calcium lactate. Other findings were normal blood pressure, high levels of plasma renin activity and serum aldosterone, a fall in blood pressure after angiotensin II antagonist infusion, blunted pressor response to angiotensin II infusion and hyperplasia of the juxtaglomerular cells. These results were compatible with Bartter's syndrome. Plasma prostaglandins E2 and F2 alpha in standing position were suppressed after indomethacin administration. To our knowledge this is thought to be the first report of a case of pseudohypoparathyroidism associated with probable Bartter's syndrome.
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