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Title: Starvation-induced ketone body production in the conscious unrestrained miniature pig. Author: Müller MJ, Paschen U, Seitz HJ. Journal: J Nutr; 1982 Jul; 112(7):1379-86. PubMed ID: 7047692. Abstract: The effects of short-term starvation (up to 5 days) on hepatic ketone body production was investigated in the conscious unrestrained miniature pig in vivo. Starvation induced an increase in arterial free fatty acid concentration (0.2-0.7 mM) with a concomitant elevation in hepatic free fatty acid extraction [-1.4-5.7 mumol/kg. minute),r = 0.53, P less than 0.005]. Ketone body production (sum of acetoacetate + beta-hydroxybutyrate) increased from 1.5 to 5.8 mumol/(kg . minute) in parallel (r = 0.71, P less than 0.0005). During starvation arterial insulin levels decreased, glucagon increased, cortisol remained unchanged and a "low T3 state' was observed. These data differ in some aspects from those reported for humans and dogs. Thus a species-specific variation in the fuel economy of the pig's body is proposed.[Abstract] [Full Text] [Related] [New Search]