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  • Title: Genes involved in the control of nuclear fusion during the sexual cycle of Saccharomyces cerevisiae.
    Author: Polaina J, Conde J.
    Journal: Mol Gen Genet; 1982; 186(2):253-8. PubMed ID: 7050632.
    Abstract:
    Mutants of Saccharomyces cerevisiae defective for nuclear fusion have been isolated. Their mutations have been characterized by meiotic analysis, dominance-recessivity and complementation. Twelve of the mutations are allelic to the previously described kar 1-1; five affect a second gene designated KAR 2 and three affect a third gene designated KAR 3. There is evidence suggesting that other two mutants are affected in a gene different from the three mentioned. Mutations in KAR 1 and KAR 2 genes are recessive and do not cause obvious effects other than the failure of the karyogamy. Mutations in KAR 3 are semidominant and do cause pleiotropic effects affecting both a mitosis and meiosis.
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