These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of lipid peroxidation on prostaglandin synthesis in rabbit kidney medulla slices.
    Author: Fujimoto Y, Fujita T.
    Journal: Biochim Biophys Acta; 1982 Jan 15; 710(1):82-6. PubMed ID: 7055599.
    Abstract:
    Ascorbic acid and Fe2+ had a more powerful stimulatory effect on the lipid peroxidation of rabbit kidney medullar slices in 0.15 M KCl/0.02 M Tris-HCl buffer than in Krebs-Henseleit buffer. The lipid peroxidation induced by ascorbic acid and Fe2+ enhanced the release of unsaturated fatty acids from tissue lipids, but inhibited medullary generation of prostaglandin E. These results suggest that the lipid peroxidation induced by ascorbic acid and Fe2+ may inhibit the formation of prostaglandin E and that this inhibitory effect may be mediated by lipid peroxides via the inhibition of prostaglandin synthetase.
    [Abstract] [Full Text] [Related] [New Search]