These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Myoadenylate deaminase deficiency or not? Observations on two brothers with exercise-induced muscle pain.
    Author: Hayes DJ, Summers BA, Morgan-Hughes JA.
    Journal: J Neurol Sci; 1982 Jan; 53(1):125-36. PubMed ID: 7057200.
    Abstract:
    This paper describes 2 brothers with increasingly severe exercise-induced muscle pain and stiffness, beginning in adolescence. Histochemical studies showed that myoadenylate deaminase activity was absent in the propositus, but present in his younger brother. Biochemical examination of muscle homogenates confirmed these findings, with enzyme activity approximately 60% of the mean control value in the younger sibling. Red cell adenylate deaminase activity was normal in both cases. The possible relationship between the clinical and biochemical findings in these patients is discussed.
    [Abstract] [Full Text] [Related] [New Search]