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  • Title: Opiate antagonists stimulate ruminal motility of conscious goats.
    Author: Maas CL.
    Journal: Eur J Pharmacol; 1982 Jan 08; 77(1):71-4. PubMed ID: 7060629.
    Abstract:
    The effect of opiate antagonists was determined on the extrinsic ruminal contractions of conscious goats. These contractions normally occur approximately once per minute. Naltrexone (greater than or equal to mg/kg, i.v.) and naloxone caused a significant increase in the frequency of ruminal contractions; morphine (0.8 mg/kg) depressed both frequency and amplitude. Naltrexone (12.5 micrograms/kg) prevented the response to morphine. These results suggest that an inhibitory opioid system is involved in the control of forestomach motility in goats.
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