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  • Title: [Differing results of direct and indirect solid phase radioimmunoassay for HBsAg in acute hepatitis (author's transl)].
    Author: Strohm WD, Legler K, Gerlich W, Stamm B, Zimmer S.
    Journal: Z Gastroenterol; 1978 Sep; 16(9):574-81. PubMed ID: 706518.
    Abstract:
    In 54 patients suffering from acute viral hepatitis the indirect solid phase radioimmunoassay (ind-SPRIA) for HBsAg was positive in 9 cases the direct solid phase radioimmunoassay (d-SPRIA) being negative. In 2 further cases ind-SPRIA was positive during several weeks but d-SPRIA only once. AntiHBc could be detected in 9 of these patients. In 7 patients the usual decrease of the transaminase activity was followed by a second elevation with prolongation of disease. The unknown factor detected by ind-SPRIA suggests a special form of acute hepatitis.
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