These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Postnatal ontogeny of evoked neuronal responses in the substantia nigra of the cat.
    Author: Fisher RS, Levine MS, Hull CD, Buchwald NA.
    Journal: Brain Res; 1982 Mar; 255(3):443-62. PubMed ID: 7066699.
    Abstract:
    Single unit extracellular responses evoked by striatal, cortical, and somatosensory stimulation were recorded in substantia nigra (SN) neurons of kittens (1-70 days of postnatal age) and adult cats. Neuronal responses to stimulation of each site were obtained throughout postnatal development. However, 4 major developmental shifts in the response of neurons were found: (1) the responsiveness of neurons to orthodromic activation increased with age; (2) the signs of the initial responses of neurons to orthodromic activation increased with age; (2) the signs of the initial responses of neurons to caudate and cortical stimulation changed with age (excitatory and inhibitory responses in kittens vs almost entirely inhibitory responses in adults); (3) the the response latencies of neurons decreased with age; (4) nigral neurons that were activated antidromically by stimulation of nigrostriatal axons showed age-related decreases in refractory periods and increases in conduction velocities.
    [Abstract] [Full Text] [Related] [New Search]