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  • Title: Isolated co-lipase deficiency in two brothers.
    Author: Hildebrand H, Borgström B, Békássy A, Erlanson-Albertsson C, Helin I.
    Journal: Gut; 1982 Mar; 23(3):243-6. PubMed ID: 7068048.
    Abstract:
    Two normally developed Assyrian brothers with isolated pancreatic co-lipase deficiency are described. They presented at the age of 5-6 years with loose stools. They had steatorrhoea, and analysis of exocrine pancreatic enzymes in the small intestine showed co-lipase deficiency, while amylase, chymotrypsin, trypsin and lipase were normal. Intraduodenal infusion of purified co-lipase improved fat digestion measured by the triolein breath test. Their steatorrhoea diminished on treatment with enteric-coated pancreatic enzymes.
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