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Title: Blood-group A and the related glycolipids of human lung. Author: Yoda Y, Makita A, Gasa S. Journal: J Biochem; 1982 Feb; 91(2):627-32. PubMed ID: 7068580. Abstract: Three glucosamine-containing sphingoglycolipids were isolated from human lung tissue of a blood group-A subject. They were hexaglycosyl, pentaglycosyl, and tetraglycosyl ceramides. The hexaglycosyl ceramide exhibited blood group-A antigenicity, and the following chemical structure was proposed on the basis of sequential glycosidase treatment and methylation analysis. (Formula: see text) The pentaglycosyl ceramide for human lung was a blood group H(O)-active glycolipid having a carbohydrate composition of Fuc : GlcNAc : Gal : Glc (1 : 1 : 2 : 1). The tetraglycosyl ceramide is probably paragloboside (lactoneotetraosyl ceramide).[Abstract] [Full Text] [Related] [New Search]