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  • Title: Enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to cysticerci of Taenia solium.
    Author: Diwan AR, Coker-Vann M, Brown P, Subianto DB, Yolken R, Desowitz R, Escobar A, Gibbs CJ, Gajdusek DC.
    Journal: Am J Trop Med Hyg; 1982 Mar; 31(2):364-9. PubMed ID: 7072900.
    Abstract:
    An enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to cysticerci of Taenia solium has been developed that employs a pork muscle antigen control for the cysticercus test antigen, somewhat improving the serological distinction between infected and uninfected subjects. Serum antibody to cysticercus was detected in 79% of classical neurocysticercosis patients from Mexico, and in 61% of a group of cysticercosis patients with an unusually rapid invasion of the central nervous system in an endemic focus of disease in Irian Jaya. Antibody was absent in a group of healthy American laboratory personnel, and in residents of a non-endemic region of Papua New Guinea. Additional test on sera from patients with other parasitic diseases showed that cross-reactivity may occur in some patients with schistosomiasis, echinococcosis, and possibly angiostrongyliasis; however, these parasites are not known to cause human infection in Irian Jaya.
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