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  • Title: Characterization of serum and liver lipids of gallstone-forming humans.
    Author: Chenouda MS, Gardner B.
    Journal: Br J Exp Pathol; 1982 Apr; 63(2):144-6. PubMed ID: 7073956.
    Abstract:
    Liver biopsy and serum specimens obtained from patients with cholesterol gallstones and from a control group were analysed for their different lipids and lipoprotein fractions. The ratio of free cholesterol to esterified cholesterol (CF/CE) was significantly (P less than 0.001) higher in the livers of gallstone-forming patients. There was no significant difference in the levels of total lipids, total cholesterol, phospholipids and glycerides. Beta-lipoprotein fraction (LDL) was higher in gallstone-forming patients. It is concluded that the decrease in esterified cholesterol of gallstone-formers may provide an important clue to an understanding of the physiology and chemistry of stone-formation in humans.
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