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  • Title: Ultrastructural changes in skeletal muscles in dengue virus-infected mice.
    Author: Nath P, Agrawal DK, Mehrotra RM.
    Journal: J Pathol; 1982 Apr; 136(4):301-5. PubMed ID: 7077434.
    Abstract:
    Dengue type 2 virus was inoculated intracerebrally in 20 adult swiss albino mice. Thigh muscles were removed after 24 h 3, 5 and 7 days after virus inoculation. Electron microscopic studies of the striated muscles show destruction of myofibrils, rarification of the sarcoplasmic reticulum network and changes in the mitochondria. Aggregates of electron-dense material as well as glycogen particles were also seen in the cytoplasm.
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