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  • Title: Acute and chronic effects of diazinon on the activities of three dehydrogenases in the digestive system of a freshwater teleost fish Channa punctatus.
    Author: Sastry KV, Malik PV.
    Journal: Toxicol Lett; 1982 Jan; 10(1):55-9. PubMed ID: 7080068.
    Abstract:
    The effect of acute exposure to LC50 for 96 h (3.1 mg/l) and chronic exposure to a sublethal concentration (0.31 mg/l) of diazinon has been studied in the liver, stomach, intestine and pyloric ceca of a freshwater teleost fish, Channa punctatus. In acute exposure succinate dehydrogenase (SDH) activity was elevated in intestine and pyloric ceca. No alteration was noted in lactate dehydrogenase activity but pyruvate dehydrogenase was inhibited in pyloric ceca. Chronic exposure resulted in inhibition of the activities of the three dehydrogenases in all the four parts at both intervals.
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