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Title: Presence of duodenopancreatic feedback in minipigs and possible interference from the bile. Author: Vantini I, Pederzoli P, Maffezzoli GF, Brocco G, Cavallini G, Pilon T, Benini P, Ederle A, Piubello W, Benini L, Ferrini S, Marchiori N, Scuro LA. Journal: Am J Gastroenterol; 1982 Mar; 77(3):154-7. PubMed ID: 7081174. Abstract: In two minipigs chronic pancreatic and duodenal fistulas, which allowed the diversion and the intestinal replacement of pancreatic secretion, were prepared. In a third minipig a chronic biliary fistula was also prepared so the bile secretion could be fed back into the intestine through a duodenal catheter. In these animals a chronic gastric fistula was made so gastric secretion could also be collected. Diversion-replacement of pure pancreatic juice and of bile were carried out in the fasting state. This study confirms the presence of a feedback regulatory mechanism in exocrine pancreatic secretion in the pig. Moreover, it suggests that bile can interfere with this phenomenon.[Abstract] [Full Text] [Related] [New Search]