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  • Title: Pharmacological modulation of neutrophil phagocytic function in a patient with recurrent sepsis, pyoderma gangrenosum and impaired phagocytosis.
    Author: Bentley-Phillips CB, Cooper RC, Hallett AF.
    Journal: Br J Dermatol; 1982 Jun; 106(6):687-95. PubMed ID: 7082573.
    Abstract:
    A 50-year-old man with recurrent life-threatening sepsis and a cutaneous condition resembling pyoderma gangrenosum, was found to have a defect of neutrophil phagocytic function. Phagocytosis could be enhanced by corticosteroids, both in vitro in a dose-dependent manner, and in vivo, when it was accompanied by rapid clinical improvement. Studies with steroid hormones and immuno-stimulatory drugs are described.
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