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  • Title: Oral contraceptives and venous thromboembolism.
    Author: Bergqvist A, Bergqvist D, Hedner U.
    Journal: Br J Obstet Gynaecol; 1982 May; 89(5):381-6. PubMed ID: 7082594.
    Abstract:
    In 58 patients with phlebographically diagnosed deep vein thrombosis during oral contraception the extension and localization of the thrombotic process was analysed in relation to the coagulation and fibrinolytic system 6 months after thrombosis. Left-sided thrombi dominated and the thrombi were more extensive and proximal on the left side. This left-sided dominance was more apparent with higher oestrogen content in the pills. The right-sided thrombi more often were the source of pulmonary embolism. In 31% of the patients a defective fibrinolytic system was found; this defect was seen more often in patients with right-sided thrombi. Only very few defects were found in the coagulation system. No patients had an antithrombin III deficiency.
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