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  • Title: Tumor-promoting phorbol esters and mezerien induce contraction in hydra.
    Author: Shiba Y.
    Journal: Experientia; 1982 Apr 15; 38(4):498-9. PubMed ID: 7084421.
    Abstract:
    12-O-tetradecanoyl phorbol-13-acetate (TPA, 1-100 ng/ml) induced a reversible contraction in the hydra, Hydra japonica. Another tumor-promoting phorbol ester, phorbol-12, 13-didecanoate (PDD), and mezerein also induced contraction, but non-tumor-promoting derivatives such as 4alpha-PDD and phorbol did not.
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