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  • Title: Erythropoietin formation during hypoxia in mice with impaired responsiveness to erythropoietin induced by irradiation or 5-fluorouracil injection.
    Author: Barceló AC, Bozzini CE.
    Journal: Experientia; 1982 Apr 15; 38(4):504-5. PubMed ID: 7084423.
    Abstract:
    Plasma erythropoietin levels during continuous exposure to hypobaric hypoxia in mice with marrow aplasia induced by whole body X-irradiation of 5-fluorouracil injection were higher than in control mice similarly exposed. There findings give support to the hypothesis that a relationship exists between erythropoietin production rate and erythroid responsiveness to the hormone.
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