These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Reevaluation of projections from the mesencephalic trigeminal nucleus to the medulla and spinal cord: new projections. a combined retrograde and anterograde horseradish peroxidase study.
    Author: Ruggiero DA, Ross CA, Kumada M, Reis DJ.
    Journal: J Comp Neurol; 1982 Apr 10; 206(3):278-92. PubMed ID: 7085934.
    Abstract:
    Microinjection of horseradish peroxidase (HRP) into the medullary parvocellular reticular formation (NPvc) resulted in retrograde labeling of neurons throughout the mesencephalic trigeminal nucleus (Mes V). Labeled cells were large and ovoid and were distributed primarily in the expanded pontine part of the nucleus. However, none of the small neurons in Mes V were labeled. Injections of HRP made into adjacent brainstem structures including the nucleus gigantocellularis, ventrolateral reticular formation, vestibular complex, and the spinal trigeminal nucleus failed to label neurons in Mes V. Injections made into the medullary raphe and into regions reported to receive inputs from Mes V--spinal cord, nucleus tractus solitarius, hypoglossal nucleus, and facial nucleus--were also not followed by transport to Mes V. Anterograde axonal transport of HRP from the region of reticular formation innervated by Mes V also labeled axons projecting to Mes V and to visceral and somatic sensorimotor nuclei in the lower brainstem. Recent reports of afferents from the amygdala to Mes V suggest that reflexes involving the mesencephalic trigeminal nucleus might be modulated by signals from limbic and autonomic as well as somatic centers in the brain.
    [Abstract] [Full Text] [Related] [New Search]