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  • Title: [Antibiotic formation from a pyrimidine base group and an aminoglycoside group by a Streptomyces coeruleoaurantiacus sp. nov. culture].
    Author: Gauze GF, Preobrazhenskaia TP, Terekhova LP, Maksimova TS, Avericheva LN.
    Journal: Antibiotiki; 1982 Apr; 27(4):243-7. PubMed ID: 7092197.
    Abstract:
    An actinomycete strain 4009 was isolated from a soil sample collected in Volgograd. The strain showed a broad antibacterial spectrum. It produced antibiotics belonging to 2 different groups of chemical compounds, i.e. amycetin from the group of pyrimidine bases and nebramycin from the group of aminoglycosides. The antibiotic-producing organism is described as a type strain of Streptomyces coeruleoaurantiacus sp. nov. The new species is characterized by spiral spore chains, wart-like spore surface, blue aerial mycelium and dark yellow, orange-yellow or brown-orange-yellow substrate mycelium, the absence of soluble pigments on synthetic media and secretion of melanin pigments on the Tresner medium. Various conditions for submerged production of the antibiotic were studied.
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