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  • Title: Probucol: effects on the metabolism of low density and high density lipoproteins in moderate hypercholesterolaemia.
    Author: Magill P, Whiting C, Hammett F, Glick I, Miller NE, Lewis B.
    Journal: Artery; 1982; 10(2):88-94. PubMed ID: 7092581.
    Abstract:
    Seven patients with primary hypercholesterolaemia (baseline levels 7.5 to 13.1 mmol/l), and with no evidence of xanthomas, were treated with probucol 1 g daily. Plasma LDL-cholesterol decreased by 20% due to reduced LDL apo B synthetic rate. HDL-cholesterol also decreased; this fall was confined to the HDL3 subclass, while HDL2-cholesterol was unchanged.
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