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  • Title: [Conductance of model proteolipid membranes].
    Author: Badzhinian SA, Manukian KG.
    Journal: Biofizika; 1982; 27(3):450-3. PubMed ID: 7093328.
    Abstract:
    Artificial membranes were reconstructed from differently purified proteolipids (PL) of cattle brain white matter. The related lipids had different quantitative (72, 50-45 and 15-8%) and qualitative content. Conductance of the artificial membranes of all three types of PL in 0.1 M solutions of alkaline metal chlorides were 2-3 orders above that of bilayer membrane of lecithin and brain phospholipids. In all the cases the PL membranes with 85-92% protein content had the highest conductance, and those with 28% protein content--the lowest. Introduction of liposomes of PL and lecithin mixture to one side of the bilayer lecithin membrane brought about a gradual increase of its conductance up to a definite high level. The membranes made of all three types have specific conductance to monovalent cations which are arranged in the following order: Na+ greater than K+ greater than Cs+ greater than Li+.
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