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  • Title: Depressive effect of high frequency peripheral conditioning stimulation upon the nociceptive component of the human blink reflex. Lack of naloxone effect.
    Author: Willer JC, Roby A, Boulu P, Albe-Fessard D.
    Journal: Brain Res; 1982 May 06; 239(1):322-6. PubMed ID: 7093689.
    Abstract:
    High frequency (100 Hz) low intensity (2 mA) peripheral conditioning stimulation of either segmental or heterosegmental cutaneous nerves induced non-naloxone-reversible depression of the nociceptive component of the human blink reflex. Electrophysiological studies suggest that this depression is due to a local synaptic inhibitory mechanism involving convergence interactions between several cutaneous afferents onto a same internuncial pool in the trigemino-facial path.
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