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  • Title: Doxepin and cimetidine in the treatment of duodenal ulcer: an open clinical and endoscopic study.
    Author: Ruud TE, Hoff GS, Tonder M, Holter O.
    Journal: J Clin Psychiatry; 1982 Aug; 43(8 Pt 2):56-60. PubMed ID: 7096279.
    Abstract:
    In an open clinical endoscopic study, 50 patients with duodenal ulcer showed no significant difference in ulcer healing during a 6-week treatment period with doxepin HCl (50 mg h.s.) versus cimetidine (1000 mg/day in divided doses). Possible tricyclic mechanisms of action in the treatment of peptic ulcer, e.g., histamine H2 blockade, are discussed.
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