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  • Title: Distribution and diameter of large dense-cored vesicles in axon terminals in the myenteric ganglia of the mouse and hamster stomach.
    Author: Hoyes AD, Grant K, Barber P, Jagessar H.
    Journal: Neurosci Lett; 1982 May 17; 30(1):19-24. PubMed ID: 7099494.
    Abstract:
    The distribution and diameter of the large dense-cored vesicles in axon terminals in the myenteric ganglia of the mouse and hamster stomach were analyzed in electron micrographs of groups of 150 terminal profiles. In the mouse, the vesicles were proportionately more numerous and larger than in the hamster; they were also larger in terminal profiles containing more than 20% of the vesicles. There was no evidence of bimodality of the distribution curve of the proportion of large dense-cored vesicles/profile in either animal. The presence of a significant degree of skew of the distribution curves was indicative of uneven distribution of the vesicles in the terminals, and the occurrence of a significant inverse correlation between the proportion of large dense-cored vesicles/profile and both the diameter of the profiles and the total number of vesicles/profile was in agreement with subjective evidence of a tendency towards accumulation of the vesicles at the ends of the terminals.
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