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  • Title: [Effect of the nutrient medium composition on biotin biosynthesis by an Actinomyces species 313-152 culture].
    Author: Akishina RI, Voronkova VV, Pomortseva NV.
    Journal: Prikl Biokhim Mikrobiol; 1982; 18(3):339-42. PubMed ID: 7100128.
    Abstract:
    The effect of the composition of the nutrient medium on the biosynthesis of biotin by the culture Actinomyces species 313-152 was investigated. This microorganism can synthesize biotin on simple and complex media. The biotin synthesis is stimulated by oleic acid and Tween-80 utilized by the culture as a carbon source. The exogenous biotin added at concentrations of 1 x 10(-8) M to 1 x 10(-6) M to the medium containing fodder yeast hydrolyzate and Tween-80 did not inhibit the synthesis by the culture Actinomyces species 313-152.
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