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  • Title: Retard implantation tablets on a matrix base with Eudragit as a structural substance.
    Author: Korsatko W.
    Journal: Pharmazie; 1982 Apr; 37(4):272-3. PubMed ID: 7100251.
    Abstract:
    A model for prolonged availability of low concentrated drugs was successfully tested by using 7-hydroxyethyltheophylline and Eudragit RS 100 as matrix to form implant-tablets. Those tablets have the same size, same weight, same hardness, but a different concentration of the model substance and are coated with liquid Eudragit RS 100. Statistical evaluation of the different liberation rates led to a drawing of a diagram whereby a desired drug liberation up to 6 d can easily be obtained by choosing a certain drug concentration of the tablet.
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