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  • Title: Protective effects of butylated hydroxyanisole, ethoxyquin, and disulfiram on acute pyrrolizidine alkaloids poisoning in mice.
    Author: Kim HL, Jones LP.
    Journal: Res Commun Chem Pathol Pharmacol; 1982 May; 36(2):341-4. PubMed ID: 7100635.
    Abstract:
    Administration of butylated hydroxyanisole (BHA), ethoxyquin (EQ), and disulfiram (DSF) in the diet for 7 days reduced the acute toxicity of pyrrolizidine alkaloids isolated from Senecio longilobus. The LD50 values of the BHA- and EQ-fed mice were about twofold of the controls but the protective effect of DSF was inferior to that of either BHA or EQ.
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