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  • Title: Effect of oral cadmium administration to female rats before and/or during pregnancy on the metallothionein level in the fetal liver.
    Author: Sowa B, Steibert E, Gralewska K, Piekarski M.
    Journal: Toxicol Lett; 1982 May; 11(3-4):233-6. PubMed ID: 7101316.
    Abstract:
    Female Wistar rats received cadmium (Cd) in drinking water at a concentration of 100 ppm before and during pregnancy, prior to gestation only, and during gestation only. For the quantitative determination of metallothionein, the 203Hg-saturation method was used. Each of the 3 exposure treatments led to a decrease of the fatal metallothionein level, which may be due to disturbance in hepatic zinc (Zn) metabolism.
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