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  • Title: [Content of 17 beta éstradiol, progesterone and glucocorticoid receptors in patients with benign breast diseases].
    Author: Bassalyk LS, Kuz'mina ZV, Murav'eva NI, Smirnova KD, Vishniakova VV.
    Journal: Vopr Onkol; 1982; 28(7):3-6. PubMed ID: 7101825.
    Abstract:
    The levels of estradiol-17 beta, progesterone and glucocorticoids were assayed in tumor tissues from 41 patients with benign breast tumors. Histologically, 21 tumors were identified as fibroadenomas of various types, 14--as fibrous-cystic non-proliferative mastopathy and 6--proliferative mastopathy. Tumor tissue contained estradiol receptors in 51% of cases, all three types of receptors--in 7% and none of the receptors was found in 29% of tumors. The levels of estrogen and glucocorticoids in cases of benign tumors were lower than those in cancer patients. However, in proliferative fibrous-cystic mastopathy group, estrogen receptor level was higher than in the other two groups.
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