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  • Title: Acyclovir treatment of experimental herpetic keratitis in the rabbit eye.
    Author: Bauer DJ.
    Journal: Am J Med; 1982 Jul 20; 73(1A):109-11. PubMed ID: 7102698.
    Abstract:
    In the rabbit eye model of experimental herpetic keratitis a satisfactory cure was obtained with ointments containing 1 percent, 2 percent, and 3 percent acyclovir, and also with idoxuridine. Trifluorothymidine and vidarabine were less effective in the particular conditions of the experiment. A cure was also obtained with acyclovir sodium salt injected intravenously, thus demonstrating that a local infection of the eye can be treated systematically.
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