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  • Title: Fluorometrical analysis of guanidino compounds in human cerebrospinal fluid.
    Author: Mori A, Watanabe Y, Fujimoto N.
    Journal: J Neurochem; 1982 Feb; 38(2):448-50. PubMed ID: 7108550.
    Abstract:
    Guanidino compounds in CSF of 57 human subjects were determined fluorometrically after reaction with phenanthrenequinone in alkali solution, using HPLC. Creatinine (65.2 +/- 13.4 nmol/ml), arginine (24.7 +/- 6.4 nmol/ml), and homoarginine (0.7 +/- 0.3 nmol/ml) were found in all subjects. Trace amounts of guanidinosuccinic acid and guanidinoacetic acid were detected in some of the subjects. Brain guanidino compounds, taurocyamine, N-acetylarginine, and methylguanidine were not detected in CSF.
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