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  • Title: [Changes in the content of opiate-like substances in auricular electroacupuncture anesthesia of rats].
    Author: Bragin EO, Dionne R, Ng L, Moody T, Pert K.
    Journal: Vopr Med Khim; 1982; 28(4):102-5. PubMed ID: 7113049.
    Abstract:
    It was shown that auricular electro-acupuncture in rats, sufficient to induce analgesia, resulted in a significant increase of endorphins in cerebro-spinal fluid with a concomitant decrease in the basomedial hypothalamus and medial thalamus of beta-endorphin-like immunoreactivity as well as endorphin-like radioreceptor activity. In addition, the radioreceptor assay also revealed a decrease of endorphin-like radioreceptor activity in the periaqueductul gray matter. plasma levels of endorphins were not altered. Cerebro-spinal fluid contained only endogenous opiate ligand material with enkephalin-like molecular weight.
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