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  • Title: Concanavalin A receptors in normal and inflamed oesophageal epithelium. A light and electron microscopic study.
    Author: Hopwood D, Logan KR, Milne G, Bouchier IA.
    Journal: Histochemistry; 1978 Sep 15; 57(3):255-63. PubMed ID: 711514.
    Abstract:
    We have examined normal and inflamed oesophageal biopsies for the distribution of alpha-D-mannosyl and alpha-D-glucosyl residues using the concanavalin A--horse radish peroxidase--Diamino-benzidine (DAB) technique at the light and electron microscope level. Receptors were found on the epithelial surface and in the nuclear membrane and endoplasmic reticulum. A similar distribution was found with the intrusive lymphocytes and polymorphonuclear leucocytes in the inflamed state. Some of the increased intercellular debris from inflamed biopsies contained concanavalin A receptors.
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