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  • Title: [Inner ear disturbance following long-term usage of hormonal contraceptives (author's transl)].
    Author: Okulicz G.
    Journal: HNO; 1978 Oct; 26(10):330-4. PubMed ID: 711515.
    Abstract:
    Four cases of either unilateral or bilateral irreversible hearing loss are reported in young women following long-term usage of hormonal contraceptives. Two different forms of the hearing disturbance and their causes are described, taking into consideration related neurological, medical and ophthalmologic literature. From this material, guidelines for clinical practise are proposed. Irreversible hearing loss was observed in 4 women aged 19-42 years who had been treated with oral contraceptives for 8 months-10 years. Deafness progressed gradually in 2 cases, and occurred suddenly in 2 others; no predisposing conditions could be identified in any of the 4 patients. Oral contraceptives involved were Neorlest, Lyndiol, and Microgynon (1 patient each); the 4th patient had taken Sequilar, Microgynon, and Ediwal for periods of 1-4 months. Testing showed that the damage lay within the cochlea in all 4 cases. Thrombotic blockages of the blood vessels supplying the inner ear are discussed as pathophysiological mechanisms.
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