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  • Title: [Effect of inotropic factors in the postload characteristics of the heart].
    Author: Orlova TsR, Ragimov SE, Shlain VA, Sakharov MP, Trubetskoĭ AV.
    Journal: Biull Eksp Biol Med; 1982 Jun; 93(6):5-7. PubMed ID: 7115936.
    Abstract:
    It was shown in acute experiments on cats that the post-exercise characteristics of the left ventricle plotted as a dependence between the magnitudes of the maximal blood flow velocity and systolic intraventricular pressure in health and inotropic exposures are close to the linear ones. Adrenaline shifts the post-exercise characteristics upward and to the right, increasing both the maximal magnitude of the blood flow velocity at a zero pressure (velocity component) and the maximal magnitude of the pressure at a zero blood flow (force component), the latter rising to a greater extent. Calcium chloride and obsidan cause a parallel shift of the post-exercise characteristics: the force and velocity components diminish upon obsidan administration, while with CaCl2 they increase.
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