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  • Title: [Gastroesophageal reflux with respiratory manifestations. Manometric and pH-metric study].
    Author: Garay J, Arana J, Alzueta M, Zaldua J, Tovar J.
    Journal: Helv Paediatr Acta; 1982 Jun; 37(3):221-30. PubMed ID: 7118554.
    Abstract:
    Gastroesophageal reflux can be found in patients with respiratory tract disease even in the absence of vomiting. A manometric and pH-metric study carried out in 69 children with radiologic reflux (of whom 49 had respiratory symptoms) and 10 normal controls has shown: 1. lower esophageal sphincter pressure was lower in refluxing patients than in controls, but values were significant only for those with vomiting; 2. all parameters of prolonged esophageal pH-metry indicating reflux were very significantly abnormal in the group of respiratory patients who were by this respect very similar to vomiting refluxers; 3. nevertheless, one fourth to one third of these patients were manometrically and pH-metrically normal. These data confirm that there is a relationship between gastroesophageal reflux and bronchopulmonary disease. A widening of the field of antireflux therapy can be predicted for the near future, although a further definition of the indications is necessary.
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