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  • Title: Iopamidol: a non-ionic contrast agent for peripheral arteriography.
    Author: Widrich WC, Robbins AH, Rommel AJ, Andrews R.
    Journal: Radiology; 1982 Oct; 145(1):53-5. PubMed ID: 7122896.
    Abstract:
    Ten patients undergoing peripheral arteriography with iopamidol were evaluated in a carefully controlled Phase I study using a variety of objective and subjective tests of discomfort. There was minimal objective evidence of pain, and the patients reported that they perceived minor discomfort and a warm sensation during the contrast injections. Five patients who had previously undergone arteriography using 2 mg of lidocaine per ml of methylglucamine diatrizoate noted a marked decrease in discomfort when iopamidol was used. Opacification of peripheral arteries was excellent. Multiple physical examinations, chemical tests, electrocardiograms, and intra-arterial pressure recordings showed that iopamidol is safe.
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